Hereditäre Nekrotisierende Myelopathie (ENM/HNM) ISAG ✅ Only breed-relevant health data

✅ Only breed-relevant health data

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Affected dogs show regurgitation of food and water

Inheritance of the disease is relatively complex due to its autosomal dominant mode and incomplete penetrance

Mutation: MAN2B1 gene

Hereditäre Nekrotisierende Myelopathie (ENM/HNM) ISAG ✅ Only breed-relevant health dataHereditary necrotising myelopathy (HNM) is an autosomal recessive inherited neurological disease in dogs, that causes a symmetric bilateral necrotising myelopathy with tissue softening in the ventral and dorsal white matter. It is characterised by progressive ataxia and paralysis in affected dogs. The symptoms start to show in the hind limbs and later progress to tetraparalysis. The clinical signs appear around 312 months of age in most dogs and