Immerslund-Gräsbeck Syndrom (IGS) - Riesenschnauzer Einzelanalyse As a result of severe

As a result of severe symptoms affected dogs have a shorter life span

which is crucial for organogenesis

Hereditary nasal parakeratosis (HNPK) is an early onset disease that generates crusts with cracks on the nose of otherwise healthy dogs

The mutation onI-Locus does not affect the eumelanin so that the black coat and the black hair ends remain black

the dog will always transfer a copy of d allele to the offspring

Immerslund-Gräsbeck Syndrom (IGS) - Riesenschnauzer Einzelanalyse As a result of severeImerslund Grsbeck syndrome is a vitamin B12 (also known as cobalamin) deficiency characterized by its malabsorption accompanied by selective proteinuria. Vitamin B12 is water soluble vitamin, important for cell metabolism in higher organisms. Affected dogs exhibit signs of cobalamin deficiency including failure to thrive, abnormal formation of blood cells, and methyl malonic aciduria within 812 weeks of birth. Affected dogs can also exhibit