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Primary/inherited form of the disease is found in around 100 dog breeds
Die Krankheit ist eine spezifische Form einer orthokeratotischen palmoplantaren Hyperkeratose
die zu einem vollständigen Verlust der Zapfenfunktion und der Aktivität des Ionenkanals führen
Zu den Symptomen gehören erhöhte Herzfrequenz
usually within the first few weeks of a puppy's life
Neuronale Zeroidlipofuszinose (NCL-1) Rassebestimmung Primary/inherited form of the diseaseNeuronal ceroid lipofuscinoses (NCLs) are a group of heritable diseases characterized by progressive neuronal degeneration and accumulation of autofluorescent cytoplasmic inclusions in the brain, retina and other tissues. Clinical symptoms and progress of the disease include increased rates of irritability, with the possibility of outbursts of aggression, hallucinations, hyperactivity and seizures. Most animals lose their ability to coordinate
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