Kupfertoxikose (CT) - Dobermann Labrador Retriever A 3-gene DNA test helps

A 3-gene DNA test helps determine the likelihood of an individual dog developing DMS

rubbing eyes

schwere Erkrankung

It is caused by axonal swelling in the cerebellum and abnormalities in the brain stem

Disease is caused by deficiency of pyruvate dehydrogenase phosphatase 1

Kupfertoxikose (CT) - Dobermann Labrador Retriever A 3-gene DNA test helpsCopper metabolism disorders are genetic disorders of copper metabolism in the liver caused by mutations in two genes that code copper transporters ATP7A and ATP7B. The ATP7A transporter is crucial for copper transport from fibroblasts into the liver and the ATP7B is crucial for copper export from the liver. Mutations in the ATP7A result in defective ATP7A transporter so the copper cannot be properly exported from fibroblasts and imported into the