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Receptor proximal assays can include cAMP response measurements, calcium flux assays where applicable, recruitment assays that track pathway engagement, and internalization or trafficking readouts that inform residence and persistence

The dosage and frequency of therapy required depends on the clinical condition of the animal and the copper status, as assessed by blood and liver levels both before and after therapy

Stability As the acetyl group protects glutathione, it is more stable in the gastrointestinal tract (Wu et al., 2004)