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The network was anchored primarily on placebo arms, and relatively few trials directly compared active agents to each other

640 In the DPN study, tanezumab provided effective pain reduction in DPN, with no safety concerns observed

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Just as the younger age and lower comorbidity burden likely explain the more pronounced reduction in all-cause mortality observed among younger individuals, these same factors may also account for their significantly lower risk of the composite outcomecomprising acute and chronic pancreatitiscompared with older participants, who instead exhibited an increased risk

Gastro-oesophageal reflux disease Treatment summaries