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Clin Pharmacokinet 36:111 Marbury TC, Flint A, Jacobsen JB, Derving Karsbol J, Lasseter K (2017) Pharmacokinetics and tolerability of a single dose of semaglutide, a human glucagon-like peptide-1 analog, in subjects with and without renal impairment
If poorly managed, T2D can lead to severe micro- and macrovascular complications, including cardiovascular disease, nephropathy, retinopathy and neuropathy, markedly reducing quality of life and escalating healthcare costs
What remains unknown Despite encouraging data, genuine unknowns exist: Effects beyond 6-9 months of continuous use have not been formally studied in animals or humans
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doi: 10.1099/mic.0.000080 4 SchulzH
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