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2) The results of the study performed by Wekwejt et al revealed several significant neurobehavioral changes in zebrafish exposed to a short-term HF diet and the subsequent ameliorative effects of MT-II treatment

Moreover, mitochondria-targeted antioxidant Mito-Tempo alleviates diabetic tubular injury and TECs apoptosis by reducing mitochondrial double-stranded RNA release and inhibiting the activation of the PKR/eIF2 signaling pathway (109), indicating that mitochondria quality control dysfunction is a significant upstreaming point in regulating apoptosis

ICER has adapted to use any credible unpublished evidence (with safeguards) ( [49] )