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In many trials, stratified reporting by CKD stage or phenotype was absent, precluding more granular inference

Meet our doctors Last reviewed: 04 Aug 2025 Sources Efficacy of tirzepatide 5, 10 and 15 mg versus semaglutide 2 mg in patients with type 2 diabetes: An adjusted indirect treatment comparison (2022) Diabetes Obesity & Metabolism [accessed 15 June 2025] MHRA authorises diabetes drug Mounjaro (tirzepatide) for weight management and weight loss (2023) Gov.uk [accessed 15 June 2025] Mounjaro (2023) Mounjaro [accessed 15 June 2025] Mounjaro KwikPen 2.5/5/7.5/10/12.5/15 mg solution for injection in pre-filled pen (2024) EMC [accessed 15 June 2025] Semaglutide versus dulaglutide once weekly in patients with type 2 diabetes (SUSTAIN 7): a randomised, open-label, phase 3b trial (2018) The Lancet [accessed 15 June 2025] Weight loss injections NHS weight loss injections GLP-1 for weight loss Can doctors help with weight loss

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Those who progress patiently typically return stronger