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While they share a common mechanismmimicking the GLP-1 hormone to stimulate insulin secretion, suppress glucagon release, and slow gastric emptyingthey differ in their molecular structures, dosing schedules, efficacy, and side effect profiles
The advancement occurred with the creation of exenatide, originating from exendin-4, a substance found in Gila monster saliva that inherently resisted DPP-4 destruction (Furman 2012)
The American Diabetes Association recommends dose adjustments of these medications when initiating GLP-1 receptor agonists
00:17:56 Vickie Danaher As more and more GLP-1 options continue to enter the picture, remember that you can turn to our interactive GLP-1 receptor agonist comparison chart available on our Pharmacists Letter and Pharmacy Technicians Letter website
The patients who see the most consistent results are the ones whose protocols were built around actual data
