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Unlike GLP-1 agonists, the changes are compositional rather than scale-weight driven: patients may not lose significant total body weight but will show meaningful reduction in waist circumference and visceral fat volume

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More importantly, endocrinologists should work coordinately with cardiologists and pharmacologists to establish GLP-1RA-dependent and independent effects in preparation for precisely commencing therapy with GLP-1RAs in suitable targeted patient categories

Progress Review & Programme Continuation Progress is reviewed at each treatment cycle

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