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The most common adverse effects of tirzepatidenausea, diarrhea, vomiting, constipation, and abdominal painare gastrointestinal in nature and occur through the medication's effects on gastric motility and gut hormone signaling rather than biliary mechanisms

CNS Drugs (2019) 33(3):20923

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Ben notes, With an oral, solid dose, youre not having to go the route of injections, which a lot of people would prefer

The brand's materials also reference a Vitamin B Complex (B1, B2, B3, B5, B6, B12) as a supporting ingredient