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Xian et al
CBS, a heme protein, is active in the oxidized form, whereas methionine synthase is inactivated by oxidation and requires reductive methylation for reactivity (Chen and Banerjee, 1998
The cells were cultured for a further 48 h before being loaded at 37C for 6 h with 2 Ci of tritiated adenine (TRK311, Amersham, Buckinghamshire, UK) in 1 ml DMEM supplemented with 0.5% foetal bovine serum
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