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If Thrive GLP-1 clearly provided value beyond what alternatives would achieve, continuation makes sense
The intervention of the L-carnitine supplementation was well tolerated with good compliance
In every case where the committee voted yes, it did so against the written recommendation of FDA career staff, who had concluded after months of review that none of the seven substances met the agency's four-part evidentiary standard for inclusion on the 503A Bulk Drug Substances List
Weight regain is a possibility with both medications when treatment ends, which is why obesity is increasingly treated as a chronic condition that benefits from long-term, supervised care
In the relevance column it says GLP-1 cardiovascular benefits are documented in trials and may align with those risk changes
