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Abstract Since the publication of the landmark EMPA-REG OUTCOME trial, sodiumglucose cotransporter 2 (SGLT2) inhibitors have redefined the therapeutic landscape of cardiovascularkidneymetabolic disease
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Risk cannot be eliminated, but gradual dose escalation, smaller meals, slower eating, adequate hydration, moderate fat intake, regular movement, and early communication with the prescribing team may improve tolerance
There is a well reported global shortage of GLP-1 drugs
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