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DeFronzo RA (2009) From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus
Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
Rather than relying solely on willpower, these therapies help regulate appetite and metabolic signaling at the biological level
Traditional guidelines have emphasized metformin as initial treatment due to its proven safety, low cost, and cardiovascular benefits
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