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High glucose levels drive endothelial cells into a prolonged proinflammatory state, characterized by NF-B upregulation and increased expression of pro-atherogenic genes such as MCP-1 and VCAM-1 (115)
Seeing these patterns of lower use of emergency care and lower use of drugs to stop migraines or trying additional drugs to prevent migraines among people taking GLP-1 drugs for other conditions suggests that these therapies may help stabilise the disease burden in ways that we havent fully appreciated yet. The study, set to be presented at the American Academy of Neurology s annual meeting in April in Chicago, only shows an association and does not prove the drugs lower the need for emergency care for people with migraine
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