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However, several major risk factors increase the likelihood of developing melasma: Sun exposure is a significant factor in the development and worsening of melasma

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Meanwhile, it was demonstrated that obesity was significantly associated with the increased risks of numerous complications, including cardiovascular disorders, diabetes mellitus, and certain cancers [2,3,4,5]

Refined sugar drives insulin spikes and reactive oxygen species, depleting cysteine, the rate limiting amino acid your body needs to make glutathione