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Curr Nutr Rep
Proceedings (Baylor University
Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team
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Over 100 published preclinical studies have demonstrated protective and reparative effects of BPC-157 across tendon, muscle, bone, and gastrointestinal tissue
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