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Additionally, senescent cells produce matrix metalloproteinases (MMPs) and other proteolytic enzymes that disrupt the extracellular matrix, interfering with normal tissue structure and function

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Fifth, we performed the analyses using sodiumglucose cotransporter 2 (SGLT2) inhibitors as the comparator: patients with no previous use of either of the study drugs and who initiated the incretin-based drug or an SGLT2 inhibitor from 1 April 2013 and onwards were included, with the date of filling the first prescription constituting cohort entry

Which toxins are eliminated through bile