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In glioblastoma multiforme (GBM), METTL3 interacts with the C5aR1-activated Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) signaling pathway by directly binding to phosphorylated ERK1/2

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Prior to PRM analysis, data-dependent acquisition (DDA) data obtained from earlier experiments were analysed via Thermo Proteome Discoverer software (version 2.4.1) to select specific peptides of the target proteins

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