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For suspected cardiac causes, BNP or NT-proBNP testing may be helpful, while D-dimer and CT pulmonary angiography may be indicated when pulmonary embolism is suspected

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(5) To better simulate the biological effects of GLP-1R, GIPR, and GCGR agonists, we opted for the genetic variables that exhibited opposite effects on the expression of GIPR/GLP-1R and HbA1c levels (with a final effect value of multiplied 1), as well as those that maintained consistent effects on GCGR expression and HbA1c

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