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The potential gains from a localized injection, if they exist, are likely marginal compared to the catastrophic loss of efficacy from using an impure or degraded peptide
Oral weight loss treatments could help reduce hesitation in areas where needle fear is more common, while also appealing to people who are already motivated to seek treatment, but would prefer a more familiar and convenient format
doi: 10.1016/j.redox.2024.103074, 80 MaoC.LiuX.ZhangY.LeiG.YanY.LeeH.et al
Research consistently shows that people on GLP-1 medications who don't prioritize protein lose significant amounts of muscle along with fat studies suggest up to 40% of weight lost can be lean muscle mass
There may be a role for microdosing in certain scenarios, such as when side effects are not manageable or intolerable for patients, even at the lowest introductory dose
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