It works by mimicking a natural gut hormone that reduces appetite, slows digestion, and helps your body manage blood sugar more effectively
Patients should be monitored for treatment response through serial measurements of weight, waist circumference, glycemic parameters, and lipid profiles
Long-Term and Structural Risks Unregulated Cell Growth (Mitogenic Risk): Like all IGF variants, DES carries a theoretical, but serious, risk of accelerating the growth of existing or dormant cancers (for example, prostate, breast) by stimulating unwanted tissue growth in certain individuals
That said, musculoskeletal symptoms including joint discomfort, arthralgia, and back pain have been observed across the broader class of incretin-based therapies
"Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes." New England Journal of Medicine , 2016