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Found naturally in plants, animals, fungi, and certain types of bacteria, this powerful molecule is produced in high concentrations in most of the bodys cellscomparable to glucose and potassium levels (Pizzorno, 2014)

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Thus, structures of glutathionylated glutaredoxins 31,43,44,45 most likely resemble enzyme species F, whereas similar structures of complexes between reduced glutaredoxin and GSH with longer sulfursulfur distances 24,46 do not represent the interaction with GSH (but probably also resemble species F)

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This integrated approach exemplifies the closed-loop framework of theranostics, merging tumor targeting, imaging, treatment, and adaptive decision-making for individualized cancer care