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Plasma samples were collected from mice after a 12-h fasting period

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These are FDA-approved formulations of semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound)

The results differ significantly by administration route: topical serum, topical post-microneedling, and supervised subcutaneous injection produce different outcomes, with injectable 503A compounded GHK-Cu producing the most consistent and comprehensive results in clinical settings

Studies assessing ulcer healing, tissue regrowth, or restoration of normal gut architecture often need at least 2-4 weeks to show major effects