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These symptoms typically occur during treatment initiation or dose escalation and often improve over several weeks as the body adapts

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these side effects often diminish as the body adjusts, though discontinuation rates were 2124% across doses

Drugs 57:607631 Honig A, Kuyper AM, Schene AH, van Melle JP, De Jonge P, Tulner DM, Schins A, Crijns HJ, Kuijpers PM, Vossen H (2007) Treatment of post-myocardial infarction depressive disorder: a randomized, placebo-controlled trial with mirtazapine