The most common side effects observed in phase 2 clinical trials were gastrointestinal-related
Dark, leafy greens and bitter foods Rocket, chicory, Brussels sprouts, broccoli Vegetables, particularly leafy greens like Brussels sprouts and broccoli, are powerful sources of nutrients that can impact GLP-1 levels and glucose regulation within just an hour of eating, says Dr Grant
For addressing a deficiency or supporting weight loss, we typically recommend weekly or bi-weekly injections
Coskun and Urva (2022, pharmacological description) describe the engineering: modified sequence derived from native GIP, Aib2 and Aib13 substitutions resisting DPP-4, and a C20 diacid fatty-acyl chain grafted to a lysine via a gamma-glutamate linker to extend half-life to approximately 6 days
This eventually helps with digestion and overall gut health