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Transglutaminase 2 mediates hypoxia-induced selective mRNA translation via polyamination of 4EBPs

illustrated how the selective permeability of the blood-brain-barrier (BBB) and bloodCSF barrier, combined with the spatial distribution of glutathione-metabolizing enzymes, underlies region-specific vulnerability to oxidative injury in the CNS (9)

Thermal shift assay (TSA) Samples were prepared by using a final concentration of 0.25 mg/ml TGR diluted in TGR reaction buffer to the desired volume