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A mouse metabolises on a faster clock than a human, and a controlled diet in a cage is not a free-living human diet so even the week-numbers above should be read as the shape of a gradual response, not a promise that a human would see anything on the same calendar

Hiebert LM, Wice SM, McDuffie NM, Jaques LB

Real-World Evidence & Preclinical Mechanism Matrix That distinction matters because the majority of long-term responders in the dataset did not describe simple short-term pain suppression