pubmed.ncbi.nlm.nih.gov/12751049 Foster DW
Intravenous and nebulised forms are used instead
Bioavailability is still lower than injection, but for patients avoiding needles it is worth discussing with a physician
3 The diagnosis of migraine is based on clinical criteria, in particular recurrent headache attacks of unilateral location, pulsating quality, moderate or severe intensity, aggravation by routine physical activity, and association with nausea, vomiting, photophobia and phonophobia
While Tetrahexyldecyl Ascorbate is listed as the second ingredient in the INCI, there are two additional forms of the molecule, including Ascorbyl Glucoside at ingredient #6 and Ascorbic Acid which may be at about a 1% concentration