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As oxidative stress increases, further stimulation of pro-inflammatory cytokines such as TNF- and IL-1 increases and contributes to synaptic dysfunction and neuronal degeneration ( These studies suggest that the loss of antioxidant defense is an early biochemical event rather than a late-stage consequence of neuronal death
Searles Nielsen, S
A novel interaction of diethyldithiocarbamate with the glutathione/glutathione peroxidase system
There are a variety of factors that can drain your levels leaving your cells more vulnerable to damage