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The research, published Saturday in the New England Journal of Medicine, is significant because semaglutide was initially prescribed for adults with Type 2 diabetes, a condition in which cells don't respond normally to insulin, the hormone made by the pancreas

If dose escalation is repeatedly interrupted by nausea or vomiting, the issue may be tolerability rather than lack of biological effect

When pain-processing circuits remain dysregulated, restoring nervous system balance becomes foundational to breaking the chronic pain cycle

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