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Children or their care givers were asked to rate the intensity of each individual symptom on a validated 5-point Likert scale (0 indicates no problem, 1 indicates mild problem, 2 indicates moderate problem, 3 indicates severe problem and 4 indicates very severe problem)

10.1080/10715760600818789 Free Radic Res

Food and Drug Administration for human or animal diagnosis, treatment, cure, mitigation, prevention, administration, or consumption

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While timing alone is unlikely to be the sole cause, it is one piece of the optimization puzzle that is easy to adjust and test