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Dejmek A et al
Limited Clinical Data: While glutathione is widely researched for skin benefits, studies examining its impact on hair colour remain minimal
The mechanism is already active: glutathione inhibits tyrosinase, the rate-limiting enzyme in melanin synthesis, and shifts melanin production from dark eumelanin toward lighter pheomelanin
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In particular, a prominent regulatory role of protein persulfidation seems apparent, perhaps because sulfide produced by this pathway may react with oxidized thiol groups
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