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The results showed continued weight loss of approximately 2.1 kg over 12 weeks, rather than the plateau many had experienced on their previous medication
Within 180 days before and including the index date, insulin use was reported for 29.1% of patients, and 63.2% had used either one or two medications in a GLD class other than SGLT2i, most often metformin (46.4%)
However, fasting also predictably induces compensatory physiologic responses, such as increased appetite signaling and reduced energy expenditure, which may undermine long-term durability
It helps regulate immune responses and supports the activity of immune cells, including lymphocytes and macrophages
Because T4 is a small, naturally occurring peptide that functions across multiple tissues, it may offer a more practical therapeutic approach compared to complex interventions such as stem cell therapies
