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These melanin-independent photoprotection studies established that MC1R activation provides cellular UV protection through DNA repair and antioxidant mechanisms beyond the physical UV-screening function of melanin
doi: 10.1016/j.pnpbp.2010.12.017 128 MainardiM.FuscoS.GrassiC
- Nausea or stomach upset (common with oral supplements) - Mild skin rashes or itching (possible with topical use) - Temporary bloating or cramping These are usually mild and subside when dosage is adjusted or discontinued
Hepatoprotective activity of Sonchus asper in paracetamol-induced hepatic damage in rabbits
Oral formulations make long-term therapy more appealing, especially for patients hesitant about injections, and they allow broader adoption in outpatient and home-care settings
