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Brief temperature excursions during transit rarely damage lyophilized peptides

It is absorbed in much higher rates when injected than when orally ingested or inhaled

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Phase 1 study of glutaminase (GLS) inhibitor CB-839 combined with either everolimus (E) or cabozantinib (Cabo) in patients (pts) with clear cell (cc) and papillary (pap) metastatic renal cell cancer (mRCC)

Published veterinary research on the peptide contributed to understanding of its mechanisms and safety profile, though this animal data has not been directly replicated in human clinical trials