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Zhou, B., Liu, J., Kang, R., Klionsky, D

Instead, theyre exploring approaches that combine responsible prescribing, clinical oversight, and lifestyle support to improve outcomes while managing utilization and costs

Obesity as a Neuro-Metabolic Disease Key mechanisms include: Neuroendocrine dysregulation of appetite and satiety Metabolic adaptation defending higher weight Environmental and behavioral feedback loops Strong relapse tendency requiring long-term care Lifestyle alone is rarely sufficient for durable control

Front Cell Neurosci 16 Mierziak J, Burgberger M, Wojtasik W (2021) 3-Hydroxybutyrate as a metabolite and a signal molecule regulating processes of living organisms

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