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Glutathione (GSH) enhancement in a concentration-dependent manner (millimolar concentrations) in DC is directly associated with IL-12 production, which in turn favours a Th1 CD4+ T cell response, resulting in the production of IL-2, IL-12, and IFN-
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Given that the heart lacks endogenous cardiomyocyte regeneration capacity, the impact of cardiomyocyte death cannot be naturally reversed and is a primary cause of reduced cardiac function in CVDs [100,101]
Peptides can also be rapidly resynthesized by fully automated methods, and peptide screening methods are very powerful and adaptable
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