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In a second study, the procedure above was repeated but with chymotrypsin as the protease (instead of trypsin) and with glutaryl-L-phenylalanine 4-methyl-7-coumarinylamide as the substrate, and a dose response curve with chenodeoxycholate at different concentrations was constructed

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Nevertheless, this represents the reality of routine clinical practice in which many patients discontinue their treatment during follow-up