And not all studies found the same link, so the evidence is mixed
With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success. The study, Optimal Timing for Cessation of GLP-1 Agonist Before Elective Total Hip and Knee Arthroplasty, obtained data from the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA from January 1, 2018 to January 1, 2023
Additionally, as part of the EVOKE trials, there are currently phase III trials conducted by Nordisk [62] investigating the use of semaglutide in the treatment of patients with early-stage AD [63]
Biomed Pharmacother 86:514520 Jamshidzadeh A, Heidari R, Latifpour Z et al (2017b) Carnosine ameliorates liver fibrosis and hyperammonemia in cirrhotic rats
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