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ErbB2-targeted therapy response is enhanced by Cpt1a deletion in an immunocompetent ErbB2+ breast cancer GEMM Using RNA expression data from both microarray and mRNA sequencing, we confirmed that overexpression of CPT1A is a marker of poor prognosis correlating with decreased overall survival in all breast cancer patients ( p = 0.0035) and specifically in HER2+ breast tumors ( p = 0.00071) (Fig
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Its your biology pushing back
The pace feels sustainable, and Im working to maintain adequate protein and muscle mass
