Bosma PJ, Chowdhury JR, Huang TJ, Lahiri P, Elferink RP, Van Es HH et al
A particularly informative pharmacological example is provided by the diazepine derivative YL3147, a highly potent radical-trapping antioxidant that directly interrupts the chain-propagation phase of lipid peroxidation and confers robust protection in both acute and chronic murine models of doxorubicin-induced cardiomyopathy
BPC-157 is unique in its stability (survives gastric juice for 24+ hours), multi-pathway mechanism of action, and effectiveness across diverse wound types
Overview and general considerations, in The molecular and cellular biology of wound repair
The same compound that repairs a torn Achilles tendon in a rat also appears to attenuate the neurological consequences of dopamine depletion, pointing to a shared upstream mechanism that remains an active area of investigation