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Aravind P, Prasad MNV

& Fuhrmann, G

The mechanism difference creates distinct outcome characteristics - Botox eliminates expression wrinkles wherever injected through complete prevention of muscle contraction creating dramatic smoothness but also limiting natural facial animation, while peptides reduce wrinkle depth while preserving expression allowing natural emotional communication without dramatic wrinkle elimination

To address this, we generated double deletion strains lacking both gshA and either the gene coding for the periplasmic binding protein GsiB, or one of the two permease domains coding genes gsiC or gsiD

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