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Type 3 Diabetes Mellitus: A Link Between Alzheimers Disease and Type 2 Diabetes Mellitus
Abubakar M, Nama L, Ansari MA, et al
Side-effects and possible issues with long-term use of these novel agents have yet to be fully evaluated
Clinical trials demonstrate substantial weight reduction with these medications: semaglutide typically produces approximately 15% weight loss in non-diabetic patients, while tirzepatide has shown up to 22% weight loss in clinical trials
Although these trials primarily enrolled individuals with relatively low DKD risk and were not designed to evaluate kidney outcomes specifically, exploratory analyses consistently indicated slower kidney disease progression across diverse eGFR and albuminuria levels [39-44]
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