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Both compounds require subcutaneous administration for bioavailabilityoral forms degrade rapidly in gastric acid and hepatic first-pass metabolism
Due to the complicating factor of a shot and the extra cost, it seems the best route for most people is to focus on getting adequate B vitamins from food, and supplement as necessary.
For treating a deficiency, injections are usually given frequently at the start, for example, several times per week or every other day for a couple of weeks, to quickly build up body stores
In more severe cases or instances of poor absorption, regular injections might be recommended
Everyone can benefit from receiving a vitamin B12 shot
