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Cost Comparison: Real 2026 Numbers A patient paying cash for Zepbound will pay roughly $15,000 per year at pharmacy retail, or about $5,400 per year at LillyDirects $449 self-pay maintenance rate

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Loose Stools: Both can speed up or alter how your digestive tract handles waste

Heres a general timeline of expected effects: Weeks 1-4: Appetite decreases, hunger cues change, early modest weight loss Months 2-3: More consistent fat loss, especially around the belly, energy becomes more stable Month 4 and beyond: Habit formation, routines strengthen, and longer-term metabolic benefits emerge Its important to remember: GLP-1s support the processthey dont do the work alone