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Most people benefit from supplementation while on GLP-1 medications because reduced food intake makes it harder to meet daily protein and micronutrient needs through diet alone
That move can reduce pharmacy dispensing fees and repeated trips, when clinically appropriate
Cancer as a metabolic disease: implications for novel therapeutics
Oral semaglutide 50 mg taken once daily in adults with overweight or obesity (OASIS 1)
The hypothesis driving its design was straightforward but unverified at the time: that engaging GIP and GLP-1 receptors simultaneously, pathways which are normally co-secreted from the gut following a meal, would produce additive or synergistic effects on insulin secretion, gastric motility, and downstream metabolic markers beyond what either pathway could deliver alone
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