For many years, AS/axSpA was considered to be a predominantly male disease but a relatively recent study from Switzerland, shows that the male to female ratio has declined from 2.57:1 in 1980 to 1.03:1 by the end of 2016
Healthon clinicians assess each patients medical history, treatment objectives, and regulatory constraints to determine whether a compounded option is medically necessary or if an FDA-approved medication is the better choice
Baseline laboratory evaluation should include HbA1c (for diabetes indication), renal function, and lipid panel
The second-line ADMs included GLP1-R agonists, sulfonylureas, dipeptidyl peptidase-4 (DPP-4) inhibitors, or sodium-glucose cotransporter 2 (SGLT2) inhibitors
These receptors are found in different tissues throughout the body, including the pancreas, brain, heart, and gastrointestinal tract